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抑癌

网络tumor suppressor

抑癌

抑癌

tumor suppressor

(a) 引入抑癌（tumor suppressor）或细胞凋亡（apoptosis）基因肿瘤细胞最常见抑癌基因表现缺失的如p53，RB1，BRCA1 等。

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Objective To detect the expression of a novo tumor suppressor gene PTEN and DNA direct repair enzyme MGMT in gynecomastia .

目的观察抑癌基因 PTEN 和 DNA 直接修复酶 MGMT 在男性乳房发育症（GM ）乳腺中的表达。

5

the average inhibitory rate of the higher concentration was bigger than that of the lower concentration .

药物的平均抑癌率随药物浓度的增加而增大。

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A summary including progress in anti-carcinoma Chinese medicine and cell apoptosis was also given in this paper .

最后，本文对中药抑癌研究和细胞凋亡研究的进展作了综述。

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It offers the users information about genes which are targets for cancer-causing mutations; proto-oncogenes and tumor suppressor genes.

其为用户提供了作为引起癌症突变靶基因、原癌基因和抑癌基因的信息。

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Some of them are oncogene protein and suppressor gene protein , while some of them are involved in apoptosis, etc.

其中有的是癌基因表达蛋白，有的是抑癌基因表达蛋白，还有的则参与凋亡过程等。

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So our datas further support that ASC is an an- tioncogene, which can enhance apoptosis , and inhibit cancer development.

因此我们可以进一步证明 ASC 是一种抑癌基因，促进细胞凋亡，具有抑制肿瘤的作用。

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Among the dietary factors , genistein is a global focus because of the effects of anti-cancers in vivo and in vitro .

在各种饮食因素中，大豆异黄酮由于它的体内体外抑癌作用得到了很大的关注。

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Objective To investigate the role of anti-oncogene PTEN in the tumorigenesis and development of parotid pleomorphic adenoma .

目的探讨抑癌基因 PTEN 在腮腺多形性腺瘤的发生、发展过程中的作用。

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It is the foundation to further research anti-oncogene to extract DNA from paraffin embed constitution .

从石蜡包埋组织中提取 DNA ，是进一步研究抑癌基因的基础。

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Methods Immunohistochemistry ( S - P) was app lied to measure the expression of PTEN and PCNA in 40 cases with primary glioma .

方法应用免疫组化 S-P 法检测 40 例原发胶质瘤中抑癌基因 PTEN ，增殖细胞核抗原 PCNA 的表达。

23

We demonstrate that Chd5 functions as a tumor suppressor in vivo and implicate deletion of CHD5 in human cancer .

我们证明 Chd5 在活体中作为抑癌基因发挥作用而且在人类恶性肿瘤与 CHD5 的缺失有关。

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Maybe adiponectin has the function of antitumor .

脂联素可能具有抑癌作用。

26

Objective To explore the role of antioncogene APC protein in the development an ed progress of non-small cell lung cancer .

目的探讨抑癌基因 APC 蛋白在非小细胞肺癌发生及发展中的作用和意义。

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Furthermore , miRNAs are continuously being shown to act as both oncogenes and tumor suppressors 5.

此外，microRNA 基因还不断被证实扮演着原癌基因和抑癌基因的角色。

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Recently researchers find that a new tumor suppressor imprinted gene ARHI(NOEY2)is involved in the onset and progression of cancer .

近年来研究表明，一种新的抑癌印迹基因 ARHI （NOEY2 ）的异常参与了一些肿瘤的发生。

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Objective : To study the expression and clinical significance of PTEN in the pathogenesis of endometrial carcinoma .

目的：研究抑癌基因 PTEN 在子宫内膜癌中的表达，探讨其临床意义。

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